Blood tests allow doctors to peer into the human body to analyze people's
health. But in the future, there may be a less invasive way to obtain valuable
information about a person's health: wearable sensors that use human sweat
to look for signs of disease.
Sweat is a rich source of chemical data that could help doctors determine
what is happening inside the human body, scientists explained in a new study.
Perspiration is loaded with molecules, ranging from simple electrically charged
ions to more complex proteins, and doctors can use sweat to diagnose certain
diseases, uncover drug use and optimize athletic performance, they said.
since it's, of course, very easy to analyze — you don't have to poke
the body to get it — and it has a lot of information about one's health in it,"
said study senior author Ali Javey, an electrical engineer at the University
Commercially available wearable sensors, like the Fitbit and the Apple
Watch, track users' physical activities and some vital signs, such
on a molecular level. Now, scientists say "smart" wristbands and
headbands embedded with sweat sensors could sync data wirelessly
in real time to smartphones using Bluetooth.
Previously, studies of sweat largely relied on perspiration collected off
the body in containers that was later analyzed in a lab. Now, researchers
have devised a soft, flexible, wearable sensor array to continuously monitor
tracking of a person's health.
These devices might one day help athletes track their performance and
enable doctors to continuously monitor the health of their patients to better
personalize their medication, the scientists said.
"This could help tell athletes to take liquids or warn them they are going
through heat shock," Javey told Live Science.
lactate, sodium and potassium, as well as skin temperature. This data is
fed to a flexible board of microchips that processes these signals and
uses Bluetooth to wirelessly transmit data to a smartphone. All of these
electronics could be incorporated into either a wristband or headband.
"We have a smartphone app that plots the data from sweat in real time,"
Javey said.
The researchers tested the device on 26 men and women who
pedaled indoors on stationary bikes or ran outdoors on tracks and trails.
Sodium and potassium in sweat could help check for problems such as
sugar levels. Lactate levels could indicate blood flow problems, and skin
temperature could reveal overheating and other problems.
In addition, the skin temperature sensor helps adjust the chemical sensors
to make sure they get proper readings, the researchers said. For instance,
higher skin temperatures increase the electrical signals from glucose,
which can make it look as if people are releasing more glucose in their
sweat than they actually are.
Previous wearable sweat monitors could track only a single molecule at a
time, which could generate misleading information, the researchers said.
For example, if a lone sensor showed a drop in a molecule's level, it might
not be because that molecule's level is actually falling in a person's sweat,
but rather because sweating has stopped, the sensor has detached from
the skin or the sensor is failing. The inclusion of multiple sensors could help
shed light on what is happening to a person and the sensor array as a whole.
In the near future, the researchers hope to shrink the device's electronics
down and boost the number of molecules it monitors. Such molecules
could include heavy metals such as lead, which recently made news for
appearing in dangerously high levels in the water of Flint, Michigan,
Javey noted.
In the long term, the researchers hope to conduct large-scale studies
with their device on many volunteers. The data such work gathers could
help researchers better understand what levels of various molecules
in sweat mean for athletic performance and human health, Javey said.
The researchers have filed a patent on their work, although they are
not currently collaborating with anyone to commercialize the sensors,
Javey said.
The scientists detailed their findings in the Jan. 28 issue of the
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